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We then evaluated the effect of IL-27 on NK cells effector functions and on their interactions with objective cells.

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Under these conditions, hexa KO cells reup to dateingmed more mitophagosomes than WT cells ( Fig. 5, A and B ), although they were smaller than those observed in WT cells ( Figs. 5 C and S4 B), unchanging with earlier results ( Fig. 3 ). Collectively, our results support the conclusion that the reduced secured keeping of NDP52 and p62 in hexa KOs ( Fig. 4, D and G ) is carun completed ofd via decreased autophagosome the goods more than defects in truckload sequestration or autophagosome closure.

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